Error 0x80040E2A

Value: -2147217878 | 0x80040E2A | 2147749418

What does it mean ?

DB_E_BADREGIONHANDLE  
Region handle is invalid.
Value: 3626 | 0x0E2A | 0b0000111000101010

Where does it come from ?

FACILITY_ITF  
COM/OLE Interface management. FACILITY_ITF is designated for user-defined error codes returned from interface methods
Value: 4 | 0x004 | 0b00000100

Other Errors for FACILITY_ITF